Our research program investigates the roles that glia play in the development and function of the nervious system. Glia are known to fulfill a number of important functions during nervious system development. Glia help guide axon guidance, separate axons bundles in nerves and finally arap and insulate their associated axons and nerves. However many of the molecules and signals that mediate these roles of glia have yet to be determined. This important gives the essential role that glia play in the nervous system of all animals. Any mutation or disease that disrupts glial cell function or development results in disruption of nervous system function and can lead to apralysis or death of the animal.